Human Brain Architecture Project

The Brain Architecture Project

While the human genome has been sequenced, the architecture of the human brain, in terms of its connectivity patterns and functional subsystems, remains incompletely characterized, despite the classical origins of human neuroanatomy research.

The Brain Architecture Project is a collaborative effort based in the Mitra lab with a long term goal to produce a comprehensive draft of the connectivity matrix of the human brain, along with analytical and visualization tools. A main focus will be collation and integration of existing but fragmented information about human neuroanatomy into a comprehensive database. Data from a large-scale functional brain imaging study will be analyzed in relation to project goals, and we will also consider the architecture of rodent and non-human primate brains to exploit homologies across species. The results of the project will be made readily accessible to researchers for scientific and clinical applications.

The Brain Architecture Project is supported by the WM Keck Foundation and draws on the expertise of co-investigators in neuroanatomy (Larry Swanson, USC), human brain imaging (Hans Breiter, MGH), and analysis of connectivity graphs (John Doyle, Caltech).

Project web site: http://brainarchitecture.org

Project Members:

Partha Mitra, PI
John Doyle, co-PI (Caltech)
Hans Breiter, co-PI (MGH)
Larry Swanson, co-PI (USC)
Jay Bohland, research scientist
Caizhi Wu, postdoc

Former Project Member:

Cara Allen
John Lin, programmer
Hemant Bokil, postdoc